Research focus

We deploy various computational and experimental approaches to investigate how pathogens perceive and respond to environmental stresses. Determining their stimuli response mechanisms is crucial in understanding how pathogenic bacteria initiate infections and evolve. Our research interests revolve around Antibiotic Resistance, Stomach Cancers, Soft-Matter/Complex Fluids, and integrating Microfluidics with 3D Printing technologies.

Experimental approaches: - Total Internal Reflection Fluorescence, Förster Resonance Energy Transfer, Optical Tweezers, 3D printing, Micro-Manipulation, and Laser-Darkfield Imaging. Additionally, we employ various Microfluidics/Molecular biology/Biochemistry tools.

Computational methods:- Stochastic Simulations, Monte-Carlo/Langevin dynamics, Coarse-Grained Modeling/Statistical Mechanics. We are always in the need of people with interests in molecular-tracking/data-analysis algorithms and computerizing instrumentation.

We have received a new R01 award from the NIH. Multiple positions will be available for graduate students and postdocs in Fall, 2024 and Spring 2025. Please email Dr. Lele for information